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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45118.1Cytochrome c, class III, conserved region; InterPro IPR020942:IPR002322:IPR011031; KEGG: tye:THEYE_A1056 cytochrome c3 chain A; PFAM: Cytochrome c, class III, conserved region; SPTR: Chain A, Cytochrome C3 From Desulfomicrobium Baculatus; IMG reference gene:2505284563; PFAM: Class III cytochrome C family. (126 aa)    
Predicted Functional Partners:
AEH44421.1
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR013126:IPR001023:IPR018181; KEGG: dal:Dalk_0767 DnaK-related protein; PFAM: Heat shock protein 70; SPTR: DnaK-related protein; IMG reference gene:2505283834; PFAM: DNA-K related protein; Hsp70 protein.
  
 0.755
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.721
AEH45780.1
Hypothetical protein; KEGG: sat:SYN_01836 MreB-like ATPase involved in cell division; SPTR: Putative uncharacterized protein; IMG reference gene:2505285261.
   
 0.721
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.716
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.670
AEH45477.1
KEGG: sfu:Sfum_2762 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284939.
  
     0.666
AEH45584.1
KEGG: dps:DP0127 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285051.
  
     0.661
AEH45120.1
Hypothetical protein; InterPro IPR011031; KEGG: glo:Glov_3348 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284565.
 
     0.658
AEH45124.1
Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: sfu:Sfum_0360 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; IMG reference gene:2505284569; PFAM: MerR family regulatory protein.
  
 
 0.617
AEH45885.1
KEGG: dal:Dalk_0099 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285371.
  
     0.601
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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