Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEH45163.1Nickel transport complex, NikM subunit, transmembrane; InterPro IPR019613; KEGG: ddf:DEFDS_0032 cobalt ABC transporter substrate-binding protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Cobalt ABC transporter, substrate-binding protein; IMG reference gene:2505284610; PFAM: Nickel uptake substrate-specific transmembrane region. (281 aa)    
Predicted Functional Partners:
AEH44880.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dsa:Desal_0774 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; IMG reference gene:2505284318; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
 
  
 0.954
AEH44882.1
Cobalt ABC transporter, inner membrane subunit CbiQ; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339:IPR012809; KEGG: tye:THEYE_A1922 cobalt ABC transporter, permease protein CbiQ; PFAM: cobalt transport protein; SPTR: Cobalt ABC transporter, permease protein CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; IMG reference gene:2505284320; PFAM: Cobalt transport protein; TIGRFAM: cobalt ABC transporter, permease protein CbiQ.
 
  
 0.954
AEH44883.1
ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: dsa:Desal_3208 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; IMG reference gene:2505284321; PFAM: ABC transporter.
 
  
 0.952
AEH44879.1
Nickel transport complex, NikM subunit, transmembrane; COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: ddf:DEFDS_0032 cobalt ABC transporter substrate-binding protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Cobalt ABC transporter, substrate-binding protein; IMG reference gene:2505284317; PFAM: Nickel uptake substrate-specific transmembrane region.
  
  
 
0.927
AEH44881.1
KEGG: aco:Amico_0065 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284319.
 
     0.783
AEH45469.1
KEGG: nmu:Nmul_A0035 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284931.
  
     0.495
AEH45164.1
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; IMG reference gene:2505284611; PFAM: Beta-lactamase.
       0.489
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.489
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.489
AEH45170.1
Type IV pilus assembly PilZ; InterPro IPR011752:IPR009875; KEGG: scl:sce5854 putative type IV pilus assembly protein; PFAM: type IV pilus assembly PilZ; SPTR: Putative type IV pilus assembly protein; IMG reference gene:2505284617; PFAM: PilZ domain; TIGRFAM: Myxococcus xanthus paralogous domain TIGR02266.
 
     0.459
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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