Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45164.1COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; IMG reference gene:2505284611; PFAM: Beta-lactamase. (360 aa)    
Predicted Functional Partners:
AEH45038.1
COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: dak:DaAHT2_0978 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; SPTR: Putative uncharacterized protein; IMG reference gene:2505284481; PFAM: Protein of unknown function (DUF1343).
  
 0.981
AEH44143.1
Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: dak:DaAHT2_2367 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Glycoside hydrolase family 3 domain protein; IMG reference gene:2505283543; PFAM: Glycosyl hydrolase family 3 N terminal domain.
  
 0.962
AEH44643.1
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816; KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; IMG reference gene:2505284062; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
     
 0.912
AEH45194.1
Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: dat:HRM2_35240 MrdA; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: MrdA; TIGRFAM: penicillin-binding protein 2; IMG reference gene:2505284641; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
     
 0.911
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
 0.820
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.799
AEH44452.1
Peptidase U61 LD-carboxypeptidase A; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: dol:Dole_0590 peptidase U61 LD-carboxypeptidase A; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: Peptidase U61 LD-carboxypeptidase A; IMG reference gene:2505283865; PFAM: LD-carboxypeptidase.
 
     0.606
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR020557:IPR003031; KEGG: pca:Pcar_2418 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; IMG reference gene:2505284614; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
       0.554
AEH45169.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: sfu:Sfum_2931 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2505284616; PFAM: Sulfite exporter TauE/SafE.
       0.554
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR002314:IPR004154:IPR004516:IPR 006195; KEGG: sat:SYN_02534 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; IMG reference gene:2505284615; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
       0.551
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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