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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hslOHsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. (299 aa)    
Predicted Functional Partners:
AEH45164.1
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; IMG reference gene:2505284611; PFAM: Beta-lactamase.
       0.809
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.779
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
  
 0.639
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.638
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
  
 0.559
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR020557:IPR003031; KEGG: pca:Pcar_2418 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; IMG reference gene:2505284614; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
       0.558
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR002314:IPR004154:IPR004516:IPR 006195; KEGG: sat:SYN_02534 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; IMG reference gene:2505284615; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
       0.551
AEH45169.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: sfu:Sfum_2931 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2505284616; PFAM: Sulfite exporter TauE/SafE.
       0.551
AEH45170.1
Type IV pilus assembly PilZ; InterPro IPR011752:IPR009875; KEGG: scl:sce5854 putative type IV pilus assembly protein; PFAM: type IV pilus assembly PilZ; SPTR: Putative type IV pilus assembly protein; IMG reference gene:2505284617; PFAM: PilZ domain; TIGRFAM: Myxococcus xanthus paralogous domain TIGR02266.
       0.551
AEH43925.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
    0.545
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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