Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45184.1NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086:IPR020084:IPR020476; KEGG: geo:Geob_3053 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; IMG reference gene:2505284631; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (164 aa)    
Predicted Functional Partners:
AEH45185.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583:IPR020550; KEGG: dak:DaAHT2_0139 inositol monophosphatase; PFAM: inositol monophosphatase; SPTR: Inositol monophosphatase; IMG reference gene:2505284632; PFAM: Inositol monophosphatase family.
 
  
 0.975
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR020557:IPR003031; KEGG: pca:Pcar_2418 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; IMG reference gene:2505284614; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
      0.865
AEH45183.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: dak:DaAHT2_1538 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; IMG reference gene:2505284630; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
       0.778
mtnA
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
       0.778
gatB
glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
       0.778
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.494
AEH45188.1
Hemerythrin-like metal-binding protein; COGs: COG2703 Hemerythrin; InterPro IPR012827:IPR012312:IPR016131; KEGG: tmz:Tmz1t_1809 hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein; SPTR: Hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; IMG reference gene:2505284635; PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain.
       0.479
AEH45843.1
COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; InterPro IPR000438:IPR013838:IPR020582; KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase; IMG reference gene:2505285325; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
  
  
 0.438
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.408
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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