Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEH45194.1Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: dat:HRM2_35240 MrdA; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: MrdA; TIGRFAM: penicillin-binding protein 2; IMG reference gene:2505284641; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. (612 aa)    
Predicted Functional Partners:
AEH45195.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sat:SYN_00550 rod shape-determining protein; PFAM: cell cycle protein; SPTR: Rod shape-determining protein RodA; IMG reference gene:2505284642; PFAM: Cell cycle protein; Belongs to the SEDS family.
 0.998
AEH45192.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.973
AEH45191.1
Cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: dak:DaAHT2_1933 cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family; IMG reference gene:2505284638; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 
 
 0.959
AEH44643.1
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816; KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; IMG reference gene:2505284062; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
 
 0.957
AEH45164.1
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; IMG reference gene:2505284611; PFAM: Beta-lactamase.
     
 0.911
AEH44313.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.843
AEH45193.1
Hypothetical protein; KEGG: neu:NE2068 rod shape-determining MreD transmembrane protein; SPTR: Possible rod shape-determining MreD transmembrane protein; IMG reference gene:2505284640.
       0.778
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.689
AEH44693.1
Septum formation initiator; InterPro IPR007060; KEGG: dak:DaAHT2_0632 septum formation initiator; PFAM: Septum formation initiator; SPTR: Septum formation initiator; IMG reference gene:2505284112; PFAM: Septum formation initiator.
  
 
 0.682
AEH44801.1
Lytic transglycosylase catalytic; InterPro IPR002482:IPR008258:IPR018392; KEGG: dal:Dalk_1929 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SPTR: Lytic transglycosylase catalytic; IMG reference gene:2505284233; PFAM: Transglycosylase SLT domain; LysM domain.
 
 
 0.627
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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