Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45222.1Protein of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: dal:Dalk_1368 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein; IMG reference gene:2505284669; PFAM: Domain of unknown function DUF39. (394 aa)    
Predicted Functional Partners:
AEH44415.1
NIL domain protein; InterPro IPR018449:IPR017896:IPR017900; KEGG: sat:SYN_00800 ferridoxin; PFAM: NIL domain; SPTR: Ferridoxin; IMG reference gene:2505283827; PFAM: 4Fe-4S binding domain; NIL domain.
 
  
  0.976
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
  0.907
AEH44500.1
COGs: COG0460 Homoserine dehydrogenase; InterProIPR016204:IPR005106:IPR001342:IPR002912:IPR 019811; KEGG: sfu:Sfum_1218 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Homoserine dehydrogenase; IMG reference gene:2505283914; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
     
  0.900
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
AEH45262.1
ApbE family lipoprotein; COGs: COG2122 conserved hypothetical protein; InterPro IPR003374:IPR007183; KEGG: dal:Dalk_4001 ApbE family lipoprotein; PFAM: ApbE family lipoprotein; SPTR: ApbE family lipoprotein; IMG reference gene:2505284711; PFAM: ApbE family.
 
   
 0.810
AEH45223.1
COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: dak:DaAHT2_0620 putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Putative signal transduction protein with CBS domains; IMG reference gene:2505284670; PFAM: CBS domain.
       0.800
AEH45221.1
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR001962; KEGG: ate:Athe_1202 PP-loop domain protein; PFAM: asparagine synthase; SPTR: PP-loop domain protein; IMG reference gene:2505284668; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
       0.799
AEH45224.1
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731:IPR018709; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; PFAM: ATPase BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative uncharacterized protein; TIGRFAM: CoA-substrate-specific enzyme activase; IMG reference gene:2505284671; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharact [...]
       0.628
AEH45220.1
KEGG: nhl:Nhal_2827 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284667; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated endoribonuclease Cas6.
       0.615
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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