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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45268.1COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sat:SYN_00945 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; IMG reference gene:2505284717; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor. (480 aa)    
Predicted Functional Partners:
AEH44366.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR002078:IPR002197:IPR020441:IPR 003593; KEGG: sat:SYN_02530 two-component response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two-component response regulator; IMG reference gene:2505283773; PFAM: Response regulator receiver domain; Bacterial regulatory pro [...]
  
  
 0.947
AEH44365.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 004358:IPR005467:IPR000700; KEGG: mxa:MXAN_5785 pilin regulatory protein PilS; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Pilin regulatory protein PilS; TIGRFAM: PAS sensor protein; IMG reference gene:2505283772; PFAM: Histidine kinase-, DNA gy [...]
    
 0.906
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.880
AEH44399.1
COGs: COG0681 Signal peptidase I; InterProIPR000223:IPR019759:IPR019756:IPR019757:IPR 019758; KEGG: tye:THEYE_A0098 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; IMG reference gene:2505283811; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
  
  
 0.875
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.862
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.861
AEH45269.1
COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: dal:Dalk_1360 sigma 54 modulation protein/ribosomal protein S30EA; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; SPTR: Sigma 54 modulation protein/ribosomal protein S30EA; TIGRFAM: ribosomal subunit interface protein; IMG reference gene:2505284718; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein.
  
  
 0.844
AEH45266.1
Lipopolysaccharide transport periplasmic protein LptA; COGs: COG1934 conserved hypothetical protein; InterPro IPR014340:IPR005653; KEGG: gme:Gmet_1281 OstA-like protein; PFAM: OstA family protein; SPTR: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; IMG reference gene:2505284715; PFAM: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA.
  
  
 0.842
AEH45267.1
ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: glo:Glov_2167 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; IMG reference gene:2505284716; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
  
  
 0.841
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.838
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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