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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEH45300.1Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: dak:DaAHT2_1991 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: Dihydropteroate synthase DHPS; IMG reference gene:2505284753; PFAM: Pterin binding enzyme. (298 aa)    
Predicted Functional Partners:
AEH46032.1
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR019734:IPR003171:IPR016041:IPR013026; KEGG: dak:DaAHT2_0826 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; methylenetetrahydrofolate reductase; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285521; PFAM: Methylenetetrahydrofolate reductase; CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit.
 
 0.997
AEH46030.1
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041:IPR016218; KEGG: dak:DaAHT2_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285519; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
 0.990
AEH46031.1
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: dak:DaAHT2_0825 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; IMG reference gene:2505285520; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit.
 
  
 0.987
AEH45029.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tjr:TherJR_2661 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2505284472; PFAM: Methylene-tetrahydrofolate reductase C terminal; Methylenetetrahydrofolate reductase.
 
 
 0.974
AEH45299.1
Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: dak:DaAHT2_1982 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin; IMG reference gene:2505284752; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
 
 
 
 0.944
fhs
Formate--tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR000559:IPR020628; KEGG: dak:DaAHT2_0837 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; IMG reference gene:2505285529; PFAM: Formate--tetrahydrofolate ligase.
 
  
 0.928
AEH45313.1
InterPro IPR007202; KEGG: dak:DaAHT2_0716 Fe-S cluster domain protein; PFAM: Fe-S cluster domain protein; SPTR: Putative Fe-S cluster; IMG reference gene:2505284768; PFAM: Putative Fe-S cluster.
 
 
 
 0.869
AEH44053.1
COGs: COG3894 Uncharacterized metal-binding protein; KEGG: dol:Dole_1485 iron-sulfur cluster binding protein; SPTR: Iron-sulfur cluster binding protein; IMG reference gene:2505283451.
 
 
 
 0.738
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
   
 0.710
AEH43905.1
Methionine synthase vitamin-B12 independent; InterPro IPR002629; KEGG: dat:HRM2_37800 hypothetical protein; PFAM: Methionine synthase vitamin-B12 independent; SPTR: Putative uncharacterized protein; IMG reference gene:2505283300; PFAM: Cobalamin-independent synthase, Catalytic domain.
  
  
 0.708
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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