Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEH45309.1Redoxin domain protein; InterPro IPR013740:IPR017937:IPR017936; KEGG: dps:DP3083 cytochrome c biogenesis protein (TlpA); PFAM: Redoxin domain protein; SPTR: Related to cytochrome c biogenesis protein (TlpA); IMG reference gene:2505284764; PFAM: Redoxin. (163 aa)    
Predicted Functional Partners:
AEH45308.1
Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: sfu:Sfum_0661 creatininase; PFAM: Creatininase; SPTR: Creatininase; IMG reference gene:2505284763; PFAM: Creatinine amidohydrolase.
       0.773
AEH44835.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: dae:Dtox_2806 peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Peroxiredoxin; manually curated; selenocysteine-containing protein; IMG reference gene:2505284269; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
   
 
 0.688
AEH45307.1
KEGG: dba:Dbac_2228 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284762.
       0.525
AEH45926.1
KEGG: tye:THEYE_A1270 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285413.
  
 
 0.501
AEH44473.1
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); COGs: COG0380 Trehalose-6-phosphate synthase; InterPro IPR012766:IPR003337:IPR006379:IPR001830; KEGG: mem:Memar_2216 putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; PFAM: glycosyl transferase family 20; trehalose-phosphatase; SPTR: Alpha,alpha-trehalose-phosphate synthase (UDP-forming); TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2505283887; PFAM: Trehalose-phosphatase; Glycosyltransferase fami [...]
   
  
 0.491
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.485
AEH45295.1
Redox-active disulfide protein 2; InterPro IPR005243; KEGG: rsq:Rsph17025_1409 hypothetical protein; SPTR: Redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; IMG reference gene:2505284747; TIGRFAM: small redox-active disulfide protein 2.
   
 0.460
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.411
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
  
 0.410
cysS
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926:IPR015803:IPR001216:IPR005856:IPR 002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; IMG reference gene:2505283966; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
     
 0.406
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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