Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (345 aa)    
Predicted Functional Partners:
selA
L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.984
AEH44933.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR000103:IPR013027:IPR001327; KEGG: tye:THEYE_A0446 oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Oxidoreductase; IMG reference gene:2505284372; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
     
 0.905
AEH45021.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: tte:TTE2220 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; IMG reference gene:2505284463; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.905
AEH45097.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR000103; KEGG: dak:DaAHT2_0308 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin-disulfide reductase; IMG reference gene:2505284542; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
     
 0.905
AEH44753.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192:IPR020578; KEGG: geo:Geob_2507 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; IMG reference gene:2505284180; PFAM: Aminotransferase class-V.
  
 
 0.892
AEH45959.1
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795:IPR005829:IPR004161:IPR015190:IPR 015191:IPR005225:IPR004535; KEGG: sfu:Sfum_1220 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; PRIAM: Sulfate adenylyltransferase; SPTR: Selenocysteine-specific translation elongation factor SelB; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; IMG reference [...]
 
   
 0.840
AEH44955.1
Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: drm:Dred_1242 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; IMG reference gene:2505284394; PFAM: DsrE/DsrF-like family; SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.
 
   
 0.717
AEH45311.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 004358:IPR005467; KEGG: dat:HRM2_39140 two domain fusion protein (N:methyl-accepting chemotaxis protein-C:sensory box histidine kinase/response regulator); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator r [...]
       0.549
AEH44961.1
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR017896; KEGG: dma:DMR_26720 molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284400; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductas [...]
     
 0.477
AEH44253.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090:IPR006089; KEGG: tye:THEYE_A0567 acyl-CoA dehydrogenase, short-chain specific; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase, short-chain specific; IMG reference gene:2505283660; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
    
   0.444
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (50%) [HD]