close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45315.1Response regulator receiver and ANTAR domain protein; COGs: COG3707 Response regulator with putative antiterminator output domain; InterPro IPR001789:IPR005561:IPR008327; KEGG: rca:Rcas_3118 response regulator receiver/ANTAR domain-containing protein; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: Response regulator receiver and ANTAR domain protein; IMG reference gene:2505284770; PFAM: Response regulator receiver domain; ANTAR domain. (202 aa)    
Predicted Functional Partners:
AEH46067.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467:IPR009056; KEGG: dba:Dbac_2092 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; IMG reference gene:2505285558; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, [...]
  
     0.732
AEH44277.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: drt:Dret_0468 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensory box histidine kinase PhoR; IMG reference gene:2505283684; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
    0.707
AEH43891.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 005467; KEGG: geo:Geob_1632 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Cell cycle histidine kinase CckA; IMG reference gene:2505283286; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like A [...]
  
     0.700
AEH44443.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: sus:Acid_7874 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2505283856; PFAM: HAMP domain; Histidine kinase-, DN [...]
  
     0.695
AEH45913.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 005467; KEGG: dvm:DvMF_0701 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2505285400; PFAM: Histidine kinase-, DNA gyrase B-, [...]
  
     0.689
AEH44233.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: jde:Jden_2000 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; IMG reference gene:2505283639; PFAM: Response regulator receiver domain.
  
   
 0.685
AEH45731.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: drm:Dred_1311 sensory histidine kinase AtoS; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine-protein kinase atoS; IMG reference gene:2505285206; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
   
 0.682
AEH45001.1
Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: dma:DMR_02390 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Cell cycle histidine kinase CckA; IMG reference gene:2505284442; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
     0.677
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
   
  
 0.673
AEH44207.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: tye:THEYE_A0744 sensory transduction protein kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensory Transduction Protein Kinase; IMG reference gene:2505283612; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A ( [...]
  
     0.657
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (36%) [HD]