Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
AEH45354.1Metallophosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: mar:MAE_46320 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2505284810; PFAM: Calcineurin-like phosphoesterase. (353 aa)    
Predicted Functional Partners:
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.912
AEH45930.1
NAD pyrophosphatase/5'-nucleotidase NadN; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179:IPR004843:IPR008334:IPR006420; KEGG: dat:HRM2_09650 UshA; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; SPTR: NAD pyrophosphatase/5'-nucleotidase NadN; TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN; IMG reference gene:2505285418; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN.
   
 
 0.912
AEH44654.1
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: gsu:GSU1174 nucleoside triphosphate pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG protein; TIGRFAM: MazG family protein; IMG reference gene:2505284073; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
     
  0.900
AEH45233.1
Adenylate kinase; InterPro IPR000850; KEGG: dol:Dole_1146 adenylate kinase-like kinase; PFAM: adenylate kinase; SPTR: Adenylate kinase; IMG reference gene:2505284681; PFAM: Adenylate kinase.
     
  0.900
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
AEH45722.1
COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR003031:IPR020557:IPR019468:IPR 004769; KEGG: geo:Geob_2894 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; IMG reference gene:2505285196; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
AEH45355.1
AAA ATPase central domain protein; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: tte:TTE1784 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Uncharacterized ATPase related to the helicase subunit of the Holliday junction resolvase; IMG reference gene:2505284811; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus.
       0.525
ybeY
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. Belongs to the endoribonuclease YbeY family.
       0.401
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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