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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (340 aa)    
Predicted Functional Partners:
AEH44187.1
COGs: COG0527 Aspartokinase; InterProIPR005260:IPR001341:IPR001048:IPR002912:IPR 001057:IPR018042; KEGG: pca:Pcar_1006 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; IMG reference gene:2505283592; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.979
AEH44500.1
COGs: COG0460 Homoserine dehydrogenase; InterProIPR016204:IPR005106:IPR001342:IPR002912:IPR 019811; KEGG: sfu:Sfum_1218 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Homoserine dehydrogenase; IMG reference gene:2505283914; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
 
 0.976
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.968
AEH45222.1
Protein of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: dal:Dalk_1368 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein; IMG reference gene:2505284669; PFAM: Domain of unknown function DUF39.
    
  0.907
AEH44415.1
NIL domain protein; InterPro IPR018449:IPR017896:IPR017900; KEGG: sat:SYN_00800 ferridoxin; PFAM: NIL domain; SPTR: Ferridoxin; IMG reference gene:2505283827; PFAM: 4Fe-4S binding domain; NIL domain.
     
  0.900
AEH45376.1
Sigma 54 interacting domain protein; May be involved in recombinational repair of damaged DNA.
       0.798
AEH45377.1
Protein of unknown function DUF814; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; KEGG: dtu:Dtur_1496 protein of unknown function DUF814; SPTR: Putative uncharacterized protein; IMG reference gene:2505284835; PFAM: Domain of unknown function (DUF814); Thiamine biosynthesis protein (ThiI).
  
    0.778
AEH45374.1
KEGG: dba:Dbac_1389 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; selenocysteine-containing protein; IMG reference gene:2505284832.
       0.727
AEH45379.1
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: cak:Caul_2794 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; IMG reference gene:2505284837; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ.
  
  
 0.625
AEH45380.1
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
     
 0.607
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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