Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45388.1Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR008284:IPR001453; KEGG: pca:Pcar_1966 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; IMG reference gene:2505284846; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (164 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.994
AEH45727.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.976
AEH45708.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.973
AEH44518.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.896
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.844
AEH45387.1
Small GTP-binding protein; COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225:IPR000795:IPR004161:IPR005517:IPR 000640; KEGG: sat:SYN_02930 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Protein translation elongation factor G; TIGRFAM: small GTP-binding protein; IMG reference gene:2505284845; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, dom [...]
       0.818
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
 
      0.761
AEH45389.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015:IPR006016; KEGG: mif:Metin_0312 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; IMG reference gene:2505284847; PFAM: Universal stress protein family.
     
 0.745
AEH45561.1
Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; KEGG: tye:THEYE_A0839 molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Protein involved in biosynthesis of molybdopterin; IMG reference gene:2505285026; PFAM: MoaE protein.
  
  
 0.677
AEH46059.1
MoaD family protein; InterPro IPR003749:IPR010038; KEGG: pmo:Pmob_0384 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; TIGRFAM: MoaD family protein; IMG reference gene:2505285550; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
  
  
 0.674
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.