close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45389.1COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015:IPR006016; KEGG: mif:Metin_0312 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; IMG reference gene:2505284847; PFAM: Universal stress protein family. (143 aa)    
Predicted Functional Partners:
AEH44914.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015:IPR006016; KEGG: dau:Daud_0271 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; IMG reference gene:2505284353; PFAM: Universal stress protein family.
  
     0.768
AEH44934.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015:IPR006016; KEGG: dma:DMR_17860 putative universal stress protein; PFAM: UspA domain-containing protein; SPTR: UspA; IMG reference gene:2505284373; PFAM: Universal stress protein family.
  
     0.754
AEH45387.1
Small GTP-binding protein; COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225:IPR000795:IPR004161:IPR005517:IPR 000640; KEGG: sat:SYN_02930 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Protein translation elongation factor G; TIGRFAM: small GTP-binding protein; IMG reference gene:2505284845; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, dom [...]
     
 0.749
AEH45388.1
Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR008284:IPR001453; KEGG: pca:Pcar_1966 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; IMG reference gene:2505284846; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
       0.747
AEH45390.1
Domain of unknown function DUF1844; InterPro IPR014995; KEGG: sfu:Sfum_3650 hypothetical protein; PFAM: Domain of unknown function DUF1844; SPTR: Conserved hypothetical cytosolic protein; IMG reference gene:2505284848; PFAM: Domain of unknown function (DUF1844).
       0.532
ispE
4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.532
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.532
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
    0.497
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: rce:RC1_2898 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2505284844; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.489
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.466
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.