Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45421.1tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (255 aa)    
Predicted Functional Partners:
AEH45422.1
COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: dal:Dalk_0808 putative aminopeptidase 1; PFAM: peptidase M18 aminopeptidase I; SPTR: M18 family aminopeptidase; IMG reference gene:2505284880; PFAM: Aminopeptidase I zinc metalloprotease (M18).
       0.818
AEH44391.1
PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012089; KEGG: saf:SULAZ_1054 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; IMG reference gene:2505283803; PFAM: PP-loop family; TIGRFAM: TIGR00269 family protein; Belongs to the TtcA family.
 
  
 0.802
AEH45420.1
Ketose-bisphosphate aldolase class-II; InterPro IPR019825:IPR000771; KEGG: tye:THEYE_A1945 hypothetical protein; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Putative uncharacterized protein; IMG reference gene:2505284878; PFAM: Fructose-bisphosphate aldolase class-II.
       0.778
AEH45423.1
Hypothetical protein; COGs: COG0616 Periplasmic serine protease (ClpP class); KEGG: ddf:DEFDS_0218 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284881; PFAM: Serine dehydrogenase proteinase.
       0.773
AEH45424.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: ddf:DEFDS_0217 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; IMG reference gene:2505284882; PFAM: Rhomboid family.
       0.773
AEH45425.1
COGs: COG4030 conserved hypothetical protein; KEGG: mth:MTH402 hypothetical protein; SPTR: Putative uncharacterized protein ehaR; IMG reference gene:2505284883.
       0.773
AEH45419.1
Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.762
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.692
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
   
    0.663
AEH45343.1
COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR005996:IPR000517:IPR018038; KEGG: mcu:HMPREF0573_10320 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein l30; TIGRFAM: ribosomal protein L30; IMG reference gene:2505284799; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
   
   0.625
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.