Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45422.1COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: dal:Dalk_0808 putative aminopeptidase 1; PFAM: peptidase M18 aminopeptidase I; SPTR: M18 family aminopeptidase; IMG reference gene:2505284880; PFAM: Aminopeptidase I zinc metalloprotease (M18). (470 aa)    
Predicted Functional Partners:
AEH45421.1
tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
       0.818
AEH45425.1
COGs: COG4030 conserved hypothetical protein; KEGG: mth:MTH402 hypothetical protein; SPTR: Putative uncharacterized protein ehaR; IMG reference gene:2505284883.
 
     0.813
AEH45420.1
Ketose-bisphosphate aldolase class-II; InterPro IPR019825:IPR000771; KEGG: tye:THEYE_A1945 hypothetical protein; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Putative uncharacterized protein; IMG reference gene:2505284878; PFAM: Fructose-bisphosphate aldolase class-II.
       0.778
AEH45424.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: ddf:DEFDS_0217 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; IMG reference gene:2505284882; PFAM: Rhomboid family.
  
    0.777
AEH45423.1
Hypothetical protein; COGs: COG0616 Periplasmic serine protease (ClpP class); KEGG: ddf:DEFDS_0218 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284881; PFAM: Serine dehydrogenase proteinase.
       0.773
AEH45419.1
Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
 
    0.751
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.593
AEH45426.1
KEGG: afw:Anae109_2844 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284884.
       0.553
ybeY
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. Belongs to the endoribonuclease YbeY family.
       0.445
AEH45224.1
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731:IPR018709; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; PFAM: ATPase BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative uncharacterized protein; TIGRFAM: CoA-substrate-specific enzyme activase; IMG reference gene:2505284671; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharact [...]
       0.410
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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