Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45428.1Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR004039:IPR009040:IPR003251; KEGG: dak:DaAHT2_2069 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; IMG reference gene:2505284886; PFAM: Rubrerythrin. (190 aa)    
Predicted Functional Partners:
AEH45905.1
COGs: COG2033 Desulfoferrodoxin; InterPro IPR004462:IPR002742:IPR004793; KEGG: dak:DaAHT2_2068 desulfoferrodoxin; PFAM: Desulfoferrodoxin ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; SPTR: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin; IMG reference gene:2505285392; PFAM: Desulfoferrodoxin; Desulfoferrodoxin, N-terminal domain; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain.
 
  
 0.609
AEH44835.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: dae:Dtox_2806 peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Peroxiredoxin; manually curated; selenocysteine-containing protein; IMG reference gene:2505284269; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.571
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006168:IPR011128:IPR006109; KEGG: lbf:LBF_0334 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; IMG reference gene:2505284887; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.551
AEH45906.1
Flavodoxin/nitric oxide synthase; COGs: COG0426 flavoprotein; InterPro IPR016440:IPR008254; KEGG: dak:DaAHT2_2067 flavodoxin/nitric oxide synthase; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavodoxin/nitric oxide synthase; IMG reference gene:2505285393; PFAM: Flavodoxin; Metallo-beta-lactamase superfamily.
 
  
 0.547
AEH45232.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR006311:IPR013352:IPR004108:IPR003149:IPR 006058:IPR017900:IPR017909:IPR017896; KEGG: pth:PTH_0668 iron only hydrogenase large subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: Iron only hydrogenase large subunit, C-terminal domain; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505284680; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
      0.509
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
    
 0.417
AEH45430.1
KEGG: slp:Slip_1886 PilT protein domain protein; SPTR: PilT protein domain protein; IMG reference gene:2505284888.
       0.414
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (24%) [HD]