Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEH45444.1Hypothetical protein; KEGG: sfu:Sfum_3293 ATPase domain-containing protein; SPTR: ATP-binding region, ATPase domain protein domain protein; IMG reference gene:2505284905. (209 aa)    
Predicted Functional Partners:
AEH45442.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_0648 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; IMG reference gene:2505284903; PFAM: Response regulator receiver domain.
  
   0.818
AEH45445.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: gme:Gmet_0890 smf protein; PFAM: SMF family protein; SPTR: SMF protein; TIGRFAM: DNA protecting protein DprA; IMG reference gene:2505284906; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
       0.818
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.800
AEH45443.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006675:IPR001789:IPR003607:IPR006674; KEGG: dat:HRM2_37390 predicted two-component system transcriptional regulator; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Predicted two-component system transcriptional regulator; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:250528490 [...]
   
   0.782
AEH45441.1
COGs: COG1334 Uncharacterized flagellar protein FlaG; InterPro IPR005186; KEGG: pmx:PERMA_1619 flagellar protein FlaG; PFAM: flagellar protein FlaG protein; SPTR: Flagellar protein FlaG; IMG reference gene:2505284902; PFAM: FlaG protein.
       0.778
AEH45440.1
Hypothetical protein; KEGG: nmr:Nmar_1213 SMC domain-containing protein; SPTR: Phage major capsid protein, HK97 family; IMG reference gene:2505284901.
       0.762
AEH44943.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...]
  
 
 0.490
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
  
 
 0.485
AEH45447.1
COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: dat:HRM2_28110 putative purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: Putative purine nucleoside phosphorylase; IMG reference gene:2505284908; PFAM: Phosphorylase superfamily.
  
    0.456
AEH45062.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013656:IPR013767:IPR005467:IPR000700; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator r [...]
  
 
 0.443
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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