Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEH45479.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441:IPR001789:IPR003593:IPR002078:IPR 002197; KEGG: dak:DaAHT2_0272 putative two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Helix-turn-helix, Fis-type; IMG reference gene:2505284941; PFAM: Response regulato [...] (462 aa)    
Predicted Functional Partners:
AEH45478.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 005467:IPR000700:IPR013767; KEGG: sfu:Sfum_2763 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505284940; PFAM: Histidine kinase-, DNA gyrase B-, and HSP [...]
 
 
 
 0.822
AEH45477.1
KEGG: sfu:Sfum_2762 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284939.
       0.756
AEH45268.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sat:SYN_00945 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; IMG reference gene:2505284717; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.729
AEH45475.1
Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR001030:IPR006250:IPR020781:IPR000573; KEGG: dak:DaAHT2_1713 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Putative aconitate hydratase; TIGRFAM: aconitate hydratase; IMG reference gene:2505284937; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type.
       0.422
AEH45476.1
Protein of unknown function UPF0182; COGs: COG1615 conserved hypothetical protein; InterPro IPR005372; KEGG: gem:GM21_2279 protein of unknown function UPF0182; PFAM: protein of unknown function UPF0182; SPTR: UPF0182 protein DAMO_1249; IMG reference gene:2505284938; PFAM: Uncharacterised protein family (UPF0182).
       0.422
AEH45480.1
InterPro IPR002781; KEGG: dal:Dalk_2526 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2505284942; PFAM: Sulfite exporter TauE/SafE.
       0.419
AEH44065.1
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: sat:SYN_02837 flagellar motor switch protein; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein; TIGRFAM: flagellar motor switch protein FliM; IMG reference gene:2505283463; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
  
  
 0.416
AEH45474.1
Hypothetical protein; KEGG: dak:DaAHT2_0838 thymidylate synthase complementing protein ThyX; SPTR: Thymidylate synthase complementing protein ThyX; IMG reference gene:2505284936.
       0.412
AEH45731.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: drm:Dred_1311 sensory histidine kinase AtoS; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine-protein kinase atoS; IMG reference gene:2505285206; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
   0.404
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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