Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45499.1Protein of unknown function DUF72; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: pho:PH0152 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein PH0152; IMG reference gene:2505284961; PFAM: Protein of unknown function DUF72. (255 aa)    
Predicted Functional Partners:
AEH46051.1
Hypothetical protein; COGs: COG2248 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR014426; KEGG: afu:AF0504 hypothetical protein; SPTR: UPF0282 protein AF_0504; IMG reference gene:2505285540; PFAM: Metallo-beta-lactamase superfamily.
  
     0.773
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.738
AEH45749.1
Glycosyltransferase 28 domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR007235; KEGG: mif:Metin_0813 SMC domain protein; PFAM: Glycosyltransferase 28 domain; SPTR: DNA double-strand break repair Rad50 ATPase; IMG reference gene:2505285225.
 
     0.683
AEH45698.1
Peptidase zinc-dependent; COGs: COG1913 Zn-dependent protease; InterPro IPR012091:IPR012962; KEGG: dth:DICTH_1693 hypothetical protein; PFAM: peptidase zinc-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2505285169; PFAM: Peptidase family M54.
  
     0.668
AEH45513.1
Bacterio-opsin activator HTH domain protein; COGs: COG1318 transcriptional regulator protein; KEGG: abi:Aboo_0950 bacterio-opsin activator HTH domain protein; SPTR: Bacterio-opsin activator HTH domain protein; IMG reference gene:2505284976; TIGRFAM: probable regulatory domain.
  
     0.633
AEH45662.1
Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1194 tetratricopeptide TPR_4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2505285133.
  
     0.632
AEH44968.1
Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR010624; KEGG: aae:aq_204 hypothetical protein; PFAM: Circadian clock protein KaiC central region; SPTR: Putative uncharacterized protein; IMG reference gene:2505284407; PFAM: KaiC; TIGRFAM: KaiC domain protein, AF_0795 family.
  
     0.626
AEH44152.1
AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family.
  
     0.598
AEH45853.1
Hypothetical protein; InterPro IPR018391; KEGG: dal:Dalk_4066 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285336.
  
     0.574
AEH45947.1
InterPro IPR021136; KEGG: cjr:CJE0040 hypothetical protein; PFAM: Flagellar hook-length control protein-like, C-terminal domain; SPTR: Putative uncharacterized protein; IMG reference gene:2505285436; PFAM: Flagellar hook-length control protein FliK.
  
     0.554
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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