STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEH45522.1COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: dat:HRM2_43840 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2505284985; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain. (383 aa)    
Predicted Functional Partners:
AEH44230.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789:IPR004358:IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Two-component system sensory/r [...]
 
 0.996
AEH44228.1
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dvm:DvMF_0284 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; IMG reference gene:2505283634; PFAM: CheW-like domain.
 
 0.992
AEH44231.1
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: psl:Psta_3345 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; IMG reference gene:2505283637; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
 
 0.983
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.983
AEH44076.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsa:Desal_2598 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; IMG reference gene:2505283474; PFAM: Response regulator receiver domain.
  
  0.952
AEH44233.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: jde:Jden_2000 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; IMG reference gene:2505283639; PFAM: Response regulator receiver domain.
  
  0.936
AEH45557.1
CheD; COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; KEGG: sat:SYN_00969 chemotaxis protein that stimulates methylation of MCP proteins; SPTR: CheD, stimulates methylation of MCP proteins; IMG reference gene:2505285022; PFAM: CheD.
 
  0.918
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
 
 
 0.622
AEH45521.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR001789:IPR005467; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: PAS sensor protein; IMG reference gene:2505284984; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
  
 
 0.599
AEH45670.1
ATPase, FliI/YscN family; COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR005714:IPR003593:IPR020003:IPR004100:IPR 000194; KEGG: dak:DaAHT2_1185 flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: Flagellar protein export ATPase FliI; TIGRFAM: ATPase, FliI/YscN family; IMG reference gene:2505285141; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-bi [...]
  
   0.502
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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