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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
AEH45529.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cco:CCC13826_0386 two component transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2505284992; PFAM: Response regulator receiver domain. (118 aa)    
Predicted Functional Partners:
AEH45062.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013656:IPR013767:IPR005467:IPR000700; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator r [...]
 
 
 0.928
AEH45478.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 005467:IPR000700:IPR013767; KEGG: sfu:Sfum_2763 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505284940; PFAM: Histidine kinase-, DNA gyrase B-, and HSP [...]
 
 
 0.908
AEH44293.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 004358:IPR005467:IPR000700; KEGG: tye:THEYE_A0125 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505283700; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like [...]
 
 
 0.889
AEH44943.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...]
 
 
 0.866
AEH44230.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789:IPR004358:IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Two-component system sensory/r [...]
  
 
0.861
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
 
 
 0.842
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
 
 
 0.832
AEH44277.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: drt:Dret_0468 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensory box histidine kinase PhoR; IMG reference gene:2505283684; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
   0.822
AEH44552.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003661:IPR003594:IPR004358; KEGG: tye:THEYE_A0262 sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine kinase; IMG reference gene:2505283968; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
   0.818
AEH44013.1
Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358:IPR003594:IPR005467; KEGG: dak:DaAHT2_2152 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensory box histidine kinase/response regulator; IMG reference gene:2505283411; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
   0.817
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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