close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sfsACOGs: COG1489 DNA-binding protein stimulates sugar fermentation; InterPro IPR005224; KEGG: abi:Aboo_0871 sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; SPTR: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; manually curated; IMG reference gene:2505285002; PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; Belongs to the SfsA family. (230 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
       0.779
AEH45539.1
Hypothetical protein; InterPro IPR022265:IPR019734:IPR013026; KEGG: sus:Acid_7234 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: hypothetical protein; IMG reference gene:2505285003; TIGRFAM: TIGR03790 family protein.
       0.779
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.543
AEH45536.1
KEGG: caa:Caka_2052 protein of unknown function DUF1568; SPTR: Putative uncharacterized protein; IMG reference gene:2505285000; PFAM: Transposase IS200 like.
       0.538
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.