Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEH45555.15-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: chy:CHY_1812 fumarylacetoacetate hydrolase family protein; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: Fumarylacetoacetate hydrolase family protein; IMG reference gene:2505285020; PFAM: Fumarylacetoacetate (FAA) hydrolase family. (253 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.785
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.775
AEH45556.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001:IPR014021:IPR001650:IPR014014:IPR 011545; KEGG: ppd:Ppro_1374 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2505285021; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
       0.704
AEH44803.1
COGs: COG0077 Prephenate dehydratase; InterProIPR018528:IPR020822:IPR001086:IPR002912:IPR 008242:IPR002701; KEGG: dak:DaAHT2_0619 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase:Chorismate mutase:Amino acid-binding ACT; IMG reference gene:2505284236; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.455
AEH45557.1
CheD; COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; KEGG: sat:SYN_00969 chemotaxis protein that stimulates methylation of MCP proteins; SPTR: CheD, stimulates methylation of MCP proteins; IMG reference gene:2505285022; PFAM: CheD.
       0.455
AEH45558.1
Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR006675:IPR003607:IPR013976; KEGG: dal:Dalk_0653 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:2505285023; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG.
       0.455
cynS
Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
 
      0.418
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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