Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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AEH45558.1Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR006675:IPR003607:IPR013976; KEGG: dal:Dalk_0653 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:2505285023; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG. (285 aa)    
Predicted Functional Partners:
AEH45557.1
CheD; COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; KEGG: sat:SYN_00969 chemotaxis protein that stimulates methylation of MCP proteins; SPTR: CheD, stimulates methylation of MCP proteins; IMG reference gene:2505285022; PFAM: CheD.
 
     0.844
AEH44789.1
COGs: COG1639 signal transduction protein; InterPro IPR013976; KEGG: dar:Daro_1602 protein kinase:GAF; PFAM: Metal-dependent hydrolase HDOD; SPTR: Protein kinase:GAF; IMG reference gene:2505284220; PFAM: HDOD domain.
  
     0.769
AEH46063.1
COGs: COG1639 signal transduction protein; InterPro IPR013976; KEGG: slt:Slit_2006 serine/threonine protein kinase; PFAM: Metal-dependent hydrolase HDOD; SPTR: Serine/threonine protein kinase; IMG reference gene:2505285554; PFAM: HDOD domain.
  
     0.705
AEH45669.1
Flagellar assembly protein FliH/Type III secretion system HrpE; COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: dal:Dalk_0669 flagellar assembly protein FliH; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein FliH; IMG reference gene:2505285140; PFAM: Flagellar assembly protein FliH.
  
     0.506
AEH45556.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001:IPR014021:IPR001650:IPR014014:IPR 011545; KEGG: ppd:Ppro_1374 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2505285021; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
       0.499
AEH45944.1
COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR011491:IPR010930:IPR020013; KEGG: dal:Dalk_1015 protein of unknown function DUF1078 domain protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: fagellar hook-basal body protein; IMG reference gene:2505285433; PFAM: Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins.
  
    0.464
AEH45555.1
5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: chy:CHY_1812 fumarylacetoacetate hydrolase family protein; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: Fumarylacetoacetate hydrolase family protein; IMG reference gene:2505285020; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
       0.455
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.452
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.452
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.424
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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