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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
AEH45573.15-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: rca:Rcas_1968 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: 5-oxoprolinase (ATP-hydrolyzing); IMG reference gene:2505285040; PFAM: Hydantoinase B/oxoprolinase. (510 aa)    
Predicted Functional Partners:
AEH44410.1
5-oxoprolinase (ATP-hydrolyzing); COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: aae:aq_708 N-methylhydantoinase A; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase A; IMG reference gene:2505283822; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 0.999
AEH44427.1
5-oxoprolinase (ATP-hydrolyzing); COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: ddf:DEFDS_0768 N-methylhydantoinase A; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase A; IMG reference gene:2505283840; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 0.999
AEH44428.1
5-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: ddf:DEFDS_0769 N-methylhydantoinase B; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase B; IMG reference gene:2505283841; PFAM: Hydantoinase B/oxoprolinase.
  
  
 
0.903
AEH45572.1
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.778
AEH45574.1
Metal dependent phosphohydrolase; COGs: COG1418 HD superfamily hydrolase; InterPro IPR006675:IPR003607:IPR006674; KEGG: dol:Dole_1644 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:2505285041; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
       0.775
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.589
AEH45576.1
Type IV pilus assembly PilZ; InterPro IPR009875; KEGG: dak:DaAHT2_2549 type IV pilus assembly PilZ; PFAM: type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; IMG reference gene:2505285043; PFAM: PilZ domain.
       0.569
AEH45571.1
KEGG: fpl:Ferp_1555 paREP15, putative coiled-coil protein; SPTR: Putative coiled-coil protein; IMG reference gene:2505285038.
       0.418
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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