close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45611.1NAD-dependent epimerase/dehydratase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR001509; KEGG: mno:Mnod_5601 oxidoreductase domain protein; PFAM: NAD-dependent epimerase/dehydratase; oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; IMG reference gene:2505285078; PFAM: NAD dependent epimerase/dehydratase family; Oxidoreductase family, NAD-binding Rossmann fold. (743 aa)    
Predicted Functional Partners:
AEH45608.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: tjr:TherJR_2108 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2505285075; PFAM: Glycosyl transferases group 1.
 
  
 0.901
AEH45609.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dth:DICTH_0207 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Glycosyltransferase; IMG reference gene:2505285076; PFAM: Glycosyl transferase family 2.
 
  
 0.893
AEH45612.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ter:Tery_4771 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2505285079; PFAM: Glycosyl transferase family 2.
 
  
 0.893
AEH44592.1
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: nis:NIS_1315 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Aminotransferase; IMG reference gene:2505284009; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.873
AEH44328.1
UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...]
 
  
 0.871
AEH44606.1
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: saf:SULAZ_0364 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2505284023; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
0.870
AEH44591.1
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sfu:Sfum_0023 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; IMG reference gene:2505284008; PFAM: Xylose isomerase-like TIM barrel.
  
  
 0.866
AEH44361.1
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: dak:DaAHT2_0857 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; IMG reference gene:2505283768; PFAM: Nucleotidyl transferase.
  
 
 0.835
AEH44593.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; IMG reference gene:2505284010; PFAM: Bacteri [...]
 
  
 0.824
AEH45610.1
Sulfotransferase; InterPro IPR000863; KEGG: ter:Tery_4121 sulfotransferase; PFAM: sulfotransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2505285077; PFAM: Sulfotransferase domain.
  
  
 0.812
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.