Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45611.1NAD-dependent epimerase/dehydratase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR001509; KEGG: mno:Mnod_5601 oxidoreductase domain protein; PFAM: NAD-dependent epimerase/dehydratase; oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; IMG reference gene:2505285078; PFAM: NAD dependent epimerase/dehydratase family; Oxidoreductase family, NAD-binding Rossmann fold. (743 aa)    
Predicted Functional Partners:
AEH45608.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: tjr:TherJR_2108 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2505285075; PFAM: Glycosyl transferases group 1.
 
  
 0.886
AEH45609.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dth:DICTH_0207 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Glycosyltransferase; IMG reference gene:2505285076; PFAM: Glycosyl transferase family 2.
 
  
 0.884
AEH45612.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ter:Tery_4771 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2505285079; PFAM: Glycosyl transferase family 2.
 
  
 0.884
AEH45343.1
COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR005996:IPR000517:IPR018038; KEGG: mcu:HMPREF0573_10320 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein l30; TIGRFAM: ribosomal protein L30; IMG reference gene:2505284799; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
   
   0.825
AEH45610.1
Sulfotransferase; InterPro IPR000863; KEGG: ter:Tery_4121 sulfotransferase; PFAM: sulfotransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2505285077; PFAM: Sulfotransferase domain.
  
  
 0.807
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
   0.793
fusA-2
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
   0.793
AEH45387.1
Small GTP-binding protein; COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225:IPR000795:IPR004161:IPR005517:IPR 000640; KEGG: sat:SYN_02930 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Protein translation elongation factor G; TIGRFAM: small GTP-binding protein; IMG reference gene:2505284845; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, dom [...]
   
   0.793
AEH44593.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; IMG reference gene:2505284010; PFAM: Bacteri [...]
 
  
 0.778
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR018130:IPR005706; KEGG: drt:Dret_1941 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; IMG reference gene:2505285432; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
  
 0.771
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.