Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AEH45623.1COGs: COG2352 Phosphoenolpyruvate carboxylase; InterPro IPR001449; KEGG: mno:Mnod_4503 phosphoenolpyruvate carboxylase; SPTR: Phosphoenolpyruvate carboxylase; IMG reference gene:2505285093; Belongs to the PEPCase type 1 family. (1008 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.929
AEH44844.1
COGs: COG1038 Pyruvate carboxylase; InterPro IPR001882:IPR000891:IPR003379:IPR000089; KEGG: cts:Ctha_2637 oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; Conserved carboxylase region; pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: Oxaloacetate decarboxylase; IMG reference gene:2505284281; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.
     
 0.927
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
     
 0.927
AEH43910.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.907
AEH45275.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dak:DaAHT2_2096 pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding protein; IMG reference gene:2505284724; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
     
 0.907
AEH45915.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dvm:DvMF_0705 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate, water dikinase; IMG reference gene:2505285402; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
     
 0.907
pgk
COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911; KEGG: dak:DaAHT2_0036 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2505284726; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.881
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
   
 
 0.827
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.824
AEH45675.1
Formate dehydrogenase subunit beta; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: ddf:DEFDS_1330 formate dehydrogenase subunit beta; SPTR: Formate dehydrogenase, beta subunit; IMG reference gene:2505285146; PFAM: 4Fe-4S binding domain.
     
 0.804
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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