Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEH45631.1HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR006402:IPR006439:IPR005834; KEGG: rsd:TGRD_051 putative phosphatase/phosphohexomutase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Putative phosphatase/phosphohexomutase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2505285101; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. (222 aa)    
Predicted Functional Partners:
AEH45633.1
KEGG: mtp:Mthe_0283 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285103.
 
     0.834
AEH45632.1
RNA methylase, NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR011023:IPR018314:IPR001678; KEGG: mtp:Mthe_0282 NOL1/NOP2/sun family RNA methylase; PFAM: Fmu (Sun) domain protein; PRIAM: tRNA (cytosine-5-)-methyltransferase; SPTR: Ribosomal RNA methyltransferase NOP2; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; IMG reference gene:2505285102; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.818
AEH45952.1
Aminoglycoside phosphotransferase; COGs: COG2187 conserved hypothetical protein; InterPro IPR002575; KEGG: tye:THEYE_A1962 Uma3; PFAM: aminoglycoside phosphotransferase; SPTR: Uma3; IMG reference gene:2505285441; PFAM: Chromatin associated protein KTI12.
  
    0.736
AEH44002.1
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dak:DaAHT2_0975 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; IMG reference gene:2505283399; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
      0.682
AEH45628.1
InterPro IPR003425; KEGG: geo:Geob_1794 protein of unknown function YGGT; PFAM: protein of unknown function YGGT; SPTR: Putative uncharacterized protein; IMG reference gene:2505285098; PFAM: YGGT family.
       0.579
AEH45630.1
Protein of unknown function DUF167; COGs: COG1872 conserved hypothetical protein; InterPro IPR005228:IPR003746; KEGG: slp:Slip_0824 protein of unknown function DUF167; PFAM: protein of unknown function DUF167; SPTR: Putative uncharacterized protein; IMG reference gene:2505285100; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: TIGR00251 family protein; Belongs to the UPF0235 family.
       0.579
AEH45626.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: pca:Pcar_1231 putative ATP-binding protein in pho regulon; PFAM: PhoH family protein; SPTR: Putative ATP-binding protein in pho regulon; IMG reference gene:2505285096; PFAM: KH domain; PhoH-like protein.
     
 0.571
AEH45627.1
Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
    0.527
AEH45624.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644; KEGG: drt:Dret_2453 Cl-channel voltage-gated family protein; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SPTR: Cl-channel voltage-gated family protein; IMG reference gene:2505285094; PFAM: CBS domain; Voltage gated chloride channel.
       0.499
AEH45625.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644; KEGG: aca:ACP_0460 chloride transporter, ClC family; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Chloride transporter, ClC family; IMG reference gene:2505285095; PFAM: CBS domain; Voltage gated chloride channel.
       0.499
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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