Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45634.1COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR017896:IPR017900:IPR007516:IPR007525; KEGG: dol:Dole_1150 coenzyme F420 hydrogenase/dehydrogenase beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; IMG reference gene:2505285104; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. (367 aa)    
Predicted Functional Partners:
AEH45639.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137; KEGG: apo:Arcpr_1551 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: F420-non-reducing hydrogenase iron-sulfur subunit G; IMG reference gene:2505285109; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
  
 
 0.928
AEH44627.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR017896:IPR013027:IPR006076:IPR003813:IPR 017900; KEGG: apo:Arcpr_0774 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505284045; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Pyridine nucleotide-disulphide [...]
 
 
 0.921
AEH44167.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR003953:IPR001327:IPR003813:IPR 017896:IPR017900; KEGG: afu:AF0662 heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase delta subunit; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505283572; PFAM: [...]
  
 
 0.906
AEH45637.1
COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: apo:Arcpr_1553 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: CoB--CoM heterodisulfide reductase; IMG reference gene:2505285107; PFAM: Cysteine-rich domain; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit B.
  
 
 0.847
AEH44173.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501:IPR018194; KEGG: dps:DP0575 Ni/Fe-hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Probable Ni/Fe-hydrogenase, large subunit; IMG reference gene:2505283578; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.820
AEH45635.1
FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896:IPR017900:IPR006076; KEGG: apo:Arcpr_1555 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD dependent oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; selenocysteine-containing protein; IMG reference gene:2505285105; PFAM: 4Fe-4S binding domain.
  
 
 0.794
AEH45638.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: tye:THEYE_A1367 methyl viologen-reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl viologen-reducing hydrogenase, subunit delta; manually curated; selenocysteine-containing protein; IMG reference gene:2505285108; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.764
AEH44961.1
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR017896; KEGG: dma:DMR_26720 molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284400; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductas [...]
  
 
 0.651
AEH45636.1
COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017896:IPR017900; KEGG: apo:Arcpr_1554 heterodisulfide reductase subunit C-like protein; SPTR: Heterodisulfide reductase subunit C; IMG reference gene:2505285106; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C.
       0.647
AEH45482.1
Molybdopterin oxidoreductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: sfu:Sfum_1318 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284944; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.637
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.