Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEH45678.1Hypothetical protein; COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; InterPro IPR001849; KEGG: ddf:DEFDS_1333 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285149; PFAM: Nitrate reductase delta subunit. (200 aa)    
Predicted Functional Partners:
AEH45679.1
Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: dps:DP1772 polyferredoxins; SPTR: Related to polyferredoxins; IMG reference gene:2505285150; PFAM: 4Fe-4S binding domain.
 
     0.970
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
 
   
 0.902
AEH45675.1
Formate dehydrogenase subunit beta; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: ddf:DEFDS_1330 formate dehydrogenase subunit beta; SPTR: Formate dehydrogenase, beta subunit; IMG reference gene:2505285146; PFAM: 4Fe-4S binding domain.
 
  
 0.875
AEH45674.1
COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR006471; KEGG: nam:NAMH_1309 formate dehydrogenase subunit C; SPTR: Formate dehydrogenase subunit C; TIGRFAM: formate dehydrogenase, gamma subunit; IMG reference gene:2505285145; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
 
  
 0.867
AEH44201.1
ABC transporter, periplasmic substrate-binding protein; COGs: COG2998 ABC-type tungstate transport system permease component; KEGG: aco:Amico_1561 ABC transporter, periplasmic substrate-binding protein; SPTR: Tungstate ABC transporter, tungstate-binding protein; IMG reference gene:2505283606.
 
     0.673
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
   
 0.647
AEH44961.1
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR017896; KEGG: dma:DMR_26720 molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284400; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductas [...]
  
 
 0.639
AEH45677.1
KEGG: ddf:DEFDS_1332 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285148; TIGRFAM: formate dehydrogenase region TAT target.
       0.613
AEH45673.1
Hypothetical protein; KEGG: dps:DP1766 molybdopterin-guanine dinucleotide biosynthesis protein B; SPTR: Related to molybdopterin-guanine dinucleotide biosynthesis protein B; IMG reference gene:2505285144.
 
     0.567
AEH44200.1
DNA binding domain protein, excisionase family; COGs: COG1910 Periplasmic molybdate-binding protein/domain; InterPro IPR010093:IPR000551; KEGG: dak:DaAHT2_2633 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; IMG reference gene:2505283605; TIGRFAM: DNA binding domain, excisionase family.
 
     0.521
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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