Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
AEH45683.1Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR019818:IPR001804; KEGG: hmo:HM1_1471 isocitrate dehydrogenase, nADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; IMG reference gene:2505285154; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (408 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.960
AEH45475.1
Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR001030:IPR006250:IPR020781:IPR000573; KEGG: dak:DaAHT2_1713 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Putative aconitate hydratase; TIGRFAM: aconitate hydratase; IMG reference gene:2505284937; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type.
 
 0.933
AEH44137.1
COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804:IPR019818; KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; IMG reference gene:2505283537; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase.
 
0.857
AEH45722.1
COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR003031:IPR020557:IPR019468:IPR 004769; KEGG: geo:Geob_2894 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; IMG reference gene:2505285196; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.835
AEH43928.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR005958:IPR004838; KEGG: aba:Acid345_1458 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; TIGRFAM: tyrosine/nicotianamine aminotransferase; IMG reference gene:2505283325; PFAM: Aminotransferase class I and II; TIGRFAM: tyrosine aminotransferase, eukaryotic; tyrosine/nicotianamine aminotransferases.
   
 
 0.817
AEH45243.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; IMG reference gene:2505284692; PFAM: Aminotransferase class I and II.
   
 
 0.817
AEH46060.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: dak:DaAHT2_0099 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; IMG reference gene:2505285551; PFAM: Aminotransferase class I and II.
   
 
 0.817
AEH44086.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.813
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR020557:IPR003031; KEGG: pca:Pcar_2418 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; IMG reference gene:2505284614; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
   
 
 0.813
AEH44373.1
Fumarate lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362:IPR018951:IPR020557; KEGG: mta:Moth_1273 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarase; IMG reference gene:2505283780; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase.
     
 0.812
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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