Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45700.1COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tme:Tmel_1752 flavin reductase domain-containing protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase domain protein, FMN-binding; IMG reference gene:2505285171; PFAM: Flavin reductase like domain. (158 aa)    
Predicted Functional Partners:
AEH45701.1
Hypothetical protein; InterPro IPR013026; KEGG: dal:Dalk_1963 TPR repeat-containing protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285172; PFAM: Pilin accessory protein (PilO).
  
    0.817
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.681
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.544
AEH45698.1
Peptidase zinc-dependent; COGs: COG1913 Zn-dependent protease; InterPro IPR012091:IPR012962; KEGG: dth:DICTH_1693 hypothetical protein; PFAM: peptidase zinc-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2505285169; PFAM: Peptidase family M54.
       0.542
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
       0.468
cobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
       0.468
AEH44458.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.459
AEH45702.1
Protein of unknown function DUF2202; COGs: COG4902 conserved hypothetical protein; InterPro IPR019243; KEGG: mfs:MFS40622_1425 protein of unknown function DUF2202; PFAM: Protein of unknown function DUF2202; SPTR: Putative uncharacterized protein; IMG reference gene:2505285173; PFAM: Uncharacterized protein domain (DUF2202).
       0.450
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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