Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45721.1NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020476:IPR020084:IPR000086; KEGG: tel:tll1077 adenine glycosylase; PFAM: NUDIX hydrolase; SPTR: Adenine glycosylase; IMG reference gene:2505285195; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein. (134 aa)    
Predicted Functional Partners:
AEH45722.1
COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR003031:IPR020557:IPR019468:IPR 004769; KEGG: geo:Geob_2894 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; IMG reference gene:2505285196; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.809
AEH45718.1
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: gbm:Gbem_3532 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; IMG reference gene:2505285192; PFAM: ABC 3 transport family.
       0.778
AEH45719.1
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: bcr:BCAH187_A4415 putative cation ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: High-affinity zinc uptake system ATP-binding protein znuC; IMG reference gene:2505285193; PFAM: ABC transporter.
       0.778
AEH45720.1
Protein of unknown function DUF1282; InterPro IPR009698; KEGG: swi:Swit_3224 hypothetical protein; PFAM: protein of unknown function DUF1282; SPTR: Putative uncharacterized protein; IMG reference gene:2505285194; PFAM: Yip1 domain.
       0.778
trmH
tRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.550
AEH45724.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.549
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.494
AEH45843.1
COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; InterPro IPR000438:IPR013838:IPR020582; KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase; IMG reference gene:2505285325; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
  
  
 0.438
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.408
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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