Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEH45750.1Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: mta:Moth_1789 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Exonuclease SbcD; IMG reference gene:2505285226; PFAM: Calcineurin-like phosphoesterase. (361 aa)    
Predicted Functional Partners:
AEH45749.1
Glycosyltransferase 28 domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR007235; KEGG: mif:Metin_0813 SMC domain protein; PFAM: Glycosyltransferase 28 domain; SPTR: DNA double-strand break repair Rad50 ATPase; IMG reference gene:2505285225.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.989
AEH45053.1
NERD domain protein; InterPro IPR011528; KEGG: dba:Dbac_0218 NERD domain protein; PFAM: NERD domain protein; SPTR: NERD domain protein; IMG reference gene:2505284496; PFAM: Nuclease-related domain.
  
 0.908
AEH44547.1
InterPro IPR005797; KEGG: nmr:Nmar_1543 cytochrome b/b6 domain-containing protein; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome b/b6 domain; IMG reference gene:2505283963.
  
 
   0.827
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.825
AEH44257.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.813
AEH44493.1
Hypothetical protein; KEGG: tye:THEYE_A1137 UvrD/REP helicase domain protein, putative; SPTR: UvrD/REP helicase domain protein, putative; IMG reference gene:2505283907; PFAM: Domain of unknown function DUF83.
 
  
 0.791
AEH45662.1
Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1194 tetratricopeptide TPR_4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2505285133.
 
     0.762
AEH45853.1
Hypothetical protein; InterPro IPR018391; KEGG: dal:Dalk_4066 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285336.
  
    0.757
AEH45854.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_4068 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2505285337; PFAM: Cobalt transport protein.
  
     0.726
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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