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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45762.1COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286:IPR003084; KEGG: sat:SYN_00740 histone deacetylase family protein; PFAM: histone deacetylase superfamily; SPTR: Histone deacetylase family protein; IMG reference gene:2505285238; PFAM: Histone deacetylase domain. (347 aa)    
Predicted Functional Partners:
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.779
AEH45761.1
Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: amt:Amet_0069 precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase; IMG reference gene:2505285237; PFAM: Precorrin-8X methylmutase.
       0.779
AEH45763.1
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cti:RALTA_A2872 conserved hypothetical protein; putative antibiotic resistance protein MarC family; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: Probable multiple antibiotic resistance protein MarC; IMG reference gene:2505285239; PFAM: MarC family integral membrane protein; TIGRFAM: membrane protein, MarC family.
       0.742
AEH45853.1
Hypothetical protein; InterPro IPR018391; KEGG: dal:Dalk_4066 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285336.
    
 0.630
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: rce:RC1_2898 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2505284844; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
    
 
 0.601
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
   
 0.497
AEH45274.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424:IPR020828:IPR020829:IPR020830:IPR 010916:IPR020832:IPR020831; KEGG: dak:DaAHT2_2095 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2505284723; PFAM [...]
 
   
 0.464
AEH45764.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR004408; KEGG: dak:DaAHT2_0465 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; IMG reference gene:2505285240; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
       0.456
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
   0.433
AEH44642.1
COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: dvl:Dvul_0535 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: CBS domain protein/ACT domain protein; IMG reference gene:2505284061; PFAM: CBS domain.
  
    0.430
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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