Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45780.1Hypothetical protein; KEGG: sat:SYN_01836 MreB-like ATPase involved in cell division; SPTR: Putative uncharacterized protein; IMG reference gene:2505285261. (311 aa)    
Predicted Functional Partners:
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 0.928
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.907
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.852
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.798
AEH45783.1
KEGG: ppd:Ppro_0260 protein-disulfide isomerase; SPTR: Protein-disulfide isomerase; IMG reference gene:2505285264.
  
  
 0.786
AEH45781.1
Hypothetical protein; KEGG: dvi:Dvir_GJ22244 GJ22244 gene product from transcript GJ22244-RA; SPTR: GA18591; IMG reference gene:2505285262.
       0.773
AEH45782.1
KEGG: hth:HTH_0126 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285263.
       0.773
AEH45792.1
KEGG: sat:SYN_01873 hypothetical protein; SPTR: Hypothetical exported protein; IMG reference gene:2505285273.
  
 
 0.767
AEH45779.1
Hypothetical protein; InterPro IPR005829; KEGG: ccs:CCNA_01817 nitrogen assimilation regulatory protein NtrX; SPTR: AmphC; IMG reference gene:2505285260.
       0.762
AEH45784.1
KEGG: sat:SYN_01859 hypothetical protein; SPTR: Hypothetical membrane protein; IMG reference gene:2505285265.
       0.746
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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