Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEH45836.1TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036:IPR003148:IPR006037; KEGG: sat:SYN_02618 potassium transporter peripheral membrane component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Trk system potassium uptake protein; IMG reference gene:2505285318; PFAM: TrkA-N domain; TrkA-C domain. (451 aa)    
Predicted Functional Partners:
AEH45835.1
Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: sat:SYN_02617 trk system potassium uptake protein; PFAM: cation transporter; SPTR: Trk system potassium uptake protein; IMG reference gene:2505285317; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
 
 
 0.979
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.652
AEH45838.1
Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: mpd:MCP_0732 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: Putative uncharacterized protein; IMG reference gene:2505285320; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.
       0.646
AEH45839.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: dak:DaAHT2_1200 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; SPTR: Fe-S type hydro-lyases tartrate/fumarate beta region; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; IMG reference gene:2505285321; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region.
       0.646
AEH44807.1
H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: sat:SYN_01091 potassium uptake protein; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: K+ transporter Trk; IMG reference gene:2505284240; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
  
 
 0.632
AEH43925.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.631
AEH45561.1
Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; KEGG: tye:THEYE_A0839 molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Protein involved in biosynthesis of molybdopterin; IMG reference gene:2505285026; PFAM: MoaE protein.
   
    0.551
AEH44750.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
    0.528
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
    0.514
AEH44847.1
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2505284284; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family.
     
 0.491
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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