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query proteins and first shell of interactors
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AEH45842.1Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005479:IPR005481:IPR005482:IPR011761:IPR 011764; KEGG: dak:DaAHT2_0460 pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; PRIAM: Pyruvate carboxylase; SPTR: Pyruvate carboxylase; IMG reference gene:2505285324; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain. (464 aa)    
Predicted Functional Partners:
AEH45843.1
COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; InterPro IPR000438:IPR013838:IPR020582; KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase; IMG reference gene:2505285325; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
 
 0.999
AEH44014.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: dak:DaAHT2_1176 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2505283412; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.977
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.958
AEH45844.1
KEGG: dps:DP3087 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285326.
 
 
 0.948
AEH44844.1
COGs: COG1038 Pyruvate carboxylase; InterPro IPR001882:IPR000891:IPR003379:IPR000089; KEGG: cts:Ctha_2637 oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; Conserved carboxylase region; pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: Oxaloacetate decarboxylase; IMG reference gene:2505284281; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.
  0.944
AEH44186.1
2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675:IPR002034; KEGG: sfu:Sfum_2174 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain-containing protein; pyruvate carboxyltransferase; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; IMG reference gene:2505283591; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthas [...]
  
 
 0.939
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.939
AEH44919.1
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034:IPR000891; KEGG: dsa:Desal_0448 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; IMG reference gene:2505284358; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.939
AEH44845.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005479:IPR005481:IPR005482:IPR011761:IPR 011764; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding; IMG reference gene:2505284282; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Car [...]
  
  
 
0.921
AEH44038.1
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.909
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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