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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45844.1KEGG: dps:DP3087 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285326. (218 aa)    
Predicted Functional Partners:
AEH45843.1
COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; InterPro IPR000438:IPR013838:IPR020582; KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase; IMG reference gene:2505285325; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
 
 
 0.999
AEH45842.1
Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005479:IPR005481:IPR005482:IPR011761:IPR 011764; KEGG: dak:DaAHT2_0460 pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; PRIAM: Pyruvate carboxylase; SPTR: Pyruvate carboxylase; IMG reference gene:2505285324; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain.
 
 
 0.981
AEH45379.1
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: cak:Caul_2794 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; IMG reference gene:2505284837; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ.
  
  
 0.903
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.897
AEH44845.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005479:IPR005481:IPR005482:IPR011761:IPR 011764; KEGG: rca:Rcas_2955 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding; IMG reference gene:2505284282; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Car [...]
  
 
 0.856
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
    0.813
AEH43936.1
RimK domain protein ATP-grasp; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651:IPR011761; KEGG: dak:DaAHT2_2417 RimK domain protein ATP-grasp; PFAM: RimK domain protein ATP-grasp; SPTR: Putative uncharacterized protein; IMG reference gene:2505283333; PFAM: RimK-like ATP-grasp domain.
  
     0.712
AEH44014.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: dak:DaAHT2_1176 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2505283412; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
  
 0.706
AEH45764.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR004408; KEGG: dak:DaAHT2_0465 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; IMG reference gene:2505285240; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
   
 
 0.697
AEH44403.1
KEGG: dak:DaAHT2_0260 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283815.
  
     0.664
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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