Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45859.1Protein of unknown function DUF105; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808; KEGG: dal:Dalk_4062 protein of unknown function DUF105; PFAM: protein of unknown function DUF105; SPTR: Putative uncharacterized protein; IMG reference gene:2505285344; PFAM: Adenosylcobinamide amidohydrolase. (394 aa)    
Predicted Functional Partners:
AEH45854.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_4068 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2505285337; PFAM: Cobalt transport protein.
 
     0.633
AEH45853.1
Hypothetical protein; InterPro IPR018391; KEGG: dal:Dalk_4066 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285336.
  
     0.629
AEH45851.1
COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR011704:IPR002035:IPR003593; KEGG: cts:Ctha_2443 magnesium chelatase; PFAM: ATPase associated with various cellular activities AAA_5; von Willebrand factor type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: Magnesium chelatase; IMG reference gene:2505285334; PFAM: von Willebrand factor type A domain; AAA domain (dynein-related subfamily); TIGRFAM: magnesium chelatase ATPase subunit D.
 
     0.579
AEH45860.1
TonB-dependent receptor; COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: glo:Glov_3556 TonB-dependent receptor plug; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor plug; IMG reference gene:2505285345; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TIGRFAM: TonB-dependent vitamin B12 receptor.
 
     0.572
AEH44457.1
Magnesium chelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: adg:Adeg_1646 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Cobaltochelatase; IMG reference gene:2505283870; PFAM: CobN/Magnesium Chelatase.
 
     0.562
AEH45752.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: rrs:RoseRS_0572 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Precorrin-3 methyltransferase / precorrin-2 dehydrogenase; TIGRFAM: precorrin-3B C17-methyltransferase; IMG reference gene:2505285228; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase.
     
 0.513
AEH45754.1
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterProIPR006365:IPR000878:IPR003358:IPR012818:IPR 014008; KEGG: dal:Dalk_0449 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,1 [...]
     
 0.477
AEH45850.1
COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523:IPR003593; KEGG: adg:Adeg_0556 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: Magnesium chelatase; IMG reference gene:2505285333; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: magnesium chelatase ATPase subunit I.
 
     0.404
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (22%) [HD]