Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhDFormate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (258 aa)    
Predicted Functional Partners:
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
 
 
 
 0.786
AEH45679.1
Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: dps:DP1772 polyferredoxins; SPTR: Related to polyferredoxins; IMG reference gene:2505285150; PFAM: 4Fe-4S binding domain.
 
   
 0.747
AEH44753.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192:IPR020578; KEGG: geo:Geob_2507 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; IMG reference gene:2505284180; PFAM: Aminotransferase class-V.
  
 0.720
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
 
 
 
 0.708
AEH44518.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
   
 0.691
AEH45674.1
COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR006471; KEGG: nam:NAMH_1309 formate dehydrogenase subunit C; SPTR: Formate dehydrogenase subunit C; TIGRFAM: formate dehydrogenase, gamma subunit; IMG reference gene:2505285145; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
 
  
 0.660
AEH45678.1
Hypothetical protein; COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; InterPro IPR001849; KEGG: ddf:DEFDS_1333 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285149; PFAM: Nitrate reductase delta subunit.
 
   
 0.647
AEH44200.1
DNA binding domain protein, excisionase family; COGs: COG1910 Periplasmic molybdate-binding protein/domain; InterPro IPR010093:IPR000551; KEGG: dak:DaAHT2_2633 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; IMG reference gene:2505283605; TIGRFAM: DNA binding domain, excisionase family.
 
   
 0.620
AEH45879.1
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: dol:Dole_1440 glycosyl transferase family protein; PFAM: glycosyl transferase family 39; SPTR: Glycosyl transferase family 39; IMG reference gene:2505285365; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
       0.610
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
  
 
 0.560
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.