Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (298 aa)    
Predicted Functional Partners:
AEH45888.1
KEGG: mxa:MXAN_0742 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285374.
       0.778
AEH45890.1
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR000644:IPR002646; KEGG: tjr:TherJR_1640 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; SPTR: Polynucleotide adenylyltransferase region; IMG reference gene:2505285376; PFAM: CBS domain; Poly A polymerase head domain.
       0.778
AEH45891.1
Peptidase M50; COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: drt:Dret_0766 peptidase M50; PFAM: peptidase M50; SPTR: Peptidase M50; IMG reference gene:2505285377; PFAM: Peptidase family M50.
       0.777
AEH45886.1
Radical SAM domain protein; COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR016431:IPR007197; KEGG: gur:Gura_2282 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; IMG reference gene:2505285372; PFAM: Radical SAM superfamily.
       0.738
AEH45887.1
Metallophosphoesterase; InterPro IPR004843; KEGG: dol:Dole_0345 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2505285373; PFAM: Calcineurin-like phosphoesterase.
       0.738
AEH45885.1
KEGG: dal:Dalk_0099 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285371.
       0.607
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.568
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.550
AEH44895.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: cth:Cthe_2248 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2505284334; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
   
    0.510
AEH44813.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR004455:IPR003099; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; SPTR: Prephenate dehydrogenase; IMG reference gene:2505284246; PFAM: Prephenate dehydrogenase.
  
    0.452
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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