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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45896.1COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; InterPro IPR020536; KEGG: pfu:PF1288 putative thiamin biosynthesis protein ThiI; PFAM: Thiamine biosynthesis protein-like; SPTR: Putative thiamin biosynthesis protein thiI; IMG reference gene:2505285383; PFAM: Thiamine biosynthesis protein (ThiI). (389 aa)    
Predicted Functional Partners:
AEH44753.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192:IPR020578; KEGG: geo:Geob_2507 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; IMG reference gene:2505284180; PFAM: Aminotransferase class-V.
  
 0.975
AEH43925.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
    0.944
AEH45897.1
AIG2 family protein; COGs: COG2105 conserved hypothetical protein; InterPro IPR009288; KEGG: pmx:PERMA_0889 hypothetical protein; PFAM: AIG2 family protein; SPTR: Conserved protein; IMG reference gene:2505285384; PFAM: AIG2-like family.
 
     0.805
AEH45898.1
COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: hma:rrnAC3218 mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: Mechanosensitive ion channel; IMG reference gene:2505285385; PFAM: Mechanosensitive ion channel.
       0.779
AEH45895.1
Glycoside hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300; KEGG: pth:PTH_2228 hypothetical protein; PFAM: glycoside hydrolase family 57; SPTR: Uncharacterized conserved protein; IMG reference gene:2505285382; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57.
       0.773
AEH45632.1
RNA methylase, NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR011023:IPR018314:IPR001678; KEGG: mtp:Mthe_0282 NOL1/NOP2/sun family RNA methylase; PFAM: Fmu (Sun) domain protein; PRIAM: tRNA (cytosine-5-)-methyltransferase; SPTR: Ribosomal RNA methyltransferase NOP2; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; IMG reference gene:2505285102; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
    0.579
AEH45899.1
KEGG: caa:Caka_2052 protein of unknown function DUF1568; SPTR: Putative uncharacterized protein; IMG reference gene:2505285386; PFAM: Transposase IS200 like.
       0.535
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.421
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR005146:IPR 005147; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; IMG reference gene:2505284919; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase [...]
  
  
 0.407
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.406
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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