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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45899.1KEGG: caa:Caka_2052 protein of unknown function DUF1568; SPTR: Putative uncharacterized protein; IMG reference gene:2505285386; PFAM: Transposase IS200 like. (281 aa)    
Predicted Functional Partners:
AEH45895.1
Glycoside hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300; KEGG: pth:PTH_2228 hypothetical protein; PFAM: glycoside hydrolase family 57; SPTR: Uncharacterized conserved protein; IMG reference gene:2505285382; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57.
       0.535
AEH45896.1
COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; InterPro IPR020536; KEGG: pfu:PF1288 putative thiamin biosynthesis protein ThiI; PFAM: Thiamine biosynthesis protein-like; SPTR: Putative thiamin biosynthesis protein thiI; IMG reference gene:2505285383; PFAM: Thiamine biosynthesis protein (ThiI).
       0.535
AEH45897.1
AIG2 family protein; COGs: COG2105 conserved hypothetical protein; InterPro IPR009288; KEGG: pmx:PERMA_0889 hypothetical protein; PFAM: AIG2 family protein; SPTR: Conserved protein; IMG reference gene:2505285384; PFAM: AIG2-like family.
       0.535
AEH45898.1
COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: hma:rrnAC3218 mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: Mechanosensitive ion channel; IMG reference gene:2505285385; PFAM: Mechanosensitive ion channel.
       0.535
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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