close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45919.1Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR017900:IPR006076:IPR003953:IPR 017896; KEGG: adg:Adeg_1885 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2505285406; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase. (1005 aa)    
Predicted Functional Partners:
AEH44683.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: drm:Dred_1326 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284102; PFAM: Cysteine-rich domain.
 
 0.988
AEH45637.1
COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: apo:Arcpr_1553 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: CoB--CoM heterodisulfide reductase; IMG reference gene:2505285107; PFAM: Cysteine-rich domain; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit B.
 
 0.985
AEH45920.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: adg:Adeg_1332 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505285407; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
   0.981
AEH44682.1
4Fe-4S ferredoxin, iron-sulfur binding protein; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017896:IPR017900; KEGG: slp:Slip_2075 4Fe-4S ferredoxin, iron-sulfur binding protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding protein; manually curated; IMG reference gene:2505284101.
  
 0.980
AEH45636.1
COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017896:IPR017900; KEGG: apo:Arcpr_1554 heterodisulfide reductase subunit C-like protein; SPTR: Heterodisulfide reductase subunit C; IMG reference gene:2505285106; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C.
  
 0.974
AEH44627.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR017896:IPR013027:IPR006076:IPR003813:IPR 017900; KEGG: apo:Arcpr_0774 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505284045; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Pyridine nucleotide-disulphide [...]
  
 
0.962
AEH45921.1
InterPro IPR017900:IPR017896; KEGG: sfu:Sfum_1972 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2505285408; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus.
 
   
 0.932
AEH45635.1
FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896:IPR017900:IPR006076; KEGG: apo:Arcpr_1555 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD dependent oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; selenocysteine-containing protein; IMG reference gene:2505285105; PFAM: 4Fe-4S binding domain.
  
  
 
0.920
AEH45638.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: tye:THEYE_A1367 methyl viologen-reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl viologen-reducing hydrogenase, subunit delta; manually curated; selenocysteine-containing protein; IMG reference gene:2505285108; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
   0.911
AEH46037.1
Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR006076:IPR003953:IPR017900:IPR 017896; KEGG: dak:DaAHT2_2650 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; manually curated; selenocysteine-containing protein; IMG reference gene:2505285526; PFAM: Pyridine nu [...]
  
  
 
0.906
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.