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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45954.1HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006439; KEGG: phe:Phep_1975 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2505285443; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (233 aa)    
Predicted Functional Partners:
AEH45955.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900:IPR017896; KEGG: tpe:Tpen_1816 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2505285444; PFAM: 4Fe-4S binding domain.
       0.553
AEH45956.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: tye:THEYE_A0591 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285445; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
       0.553
AEH45957.1
KEGG: apo:Arcpr_1635 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285446.
       0.553
AEH45307.1
KEGG: dba:Dbac_2228 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284762.
  
     0.496
AEH44400.1
KEGG: dat:HRM2_20530 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283812.
  
     0.491
AEH44458.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.482
AEH44125.1
Histidine kinase HAMP region domain protein; InterPro IPR003660; KEGG: hth:HTH_1828 putative sensor with HAMP domain; PFAM: histidine kinase HAMP region domain protein; SPTR: Sensory transduction histidine kinase; IMG reference gene:2505283524; PFAM: HAMP domain.
  
     0.441
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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