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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEH45955.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900:IPR017896; KEGG: tpe:Tpen_1816 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2505285444; PFAM: 4Fe-4S binding domain. (135 aa)    
Predicted Functional Partners:
AEH45956.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: tye:THEYE_A0591 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285445; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
   0.910
AEH45957.1
KEGG: apo:Arcpr_1635 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285446.
       0.778
AEH45482.1
Molybdopterin oxidoreductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: sfu:Sfum_1318 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284944; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
   0.570
AEH44378.1
Hypothetical protein; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR000516; KEGG: slp:Slip_1532 formate dehydrogenase, putative; SPTR: Putative formate dehydrogenase; IMG reference gene:2505283785; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
  
   0.565
AEH44961.1
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR017896; KEGG: dma:DMR_26720 molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284400; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductas [...]
  
  
0.561
AEH45954.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006439; KEGG: phe:Phep_1975 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2505285443; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
       0.553
AEH45414.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: dhd:Dhaf_0260 polysulphide reductase NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase NrfD; IMG reference gene:2505284872; PFAM: Polysulphide reductase, NrfD.
  
   0.541
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.502
AEH44275.1
Hypothetical protein; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR017970; KEGG: dak:DaAHT2_2115 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283682; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
   
   0.499
AEH45674.1
COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR006471; KEGG: nam:NAMH_1309 formate dehydrogenase subunit C; SPTR: Formate dehydrogenase subunit C; TIGRFAM: formate dehydrogenase, gamma subunit; IMG reference gene:2505285145; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
   
   0.499
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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